DODGEN Methionine Process Technology

Introduction to Rare Earth Catalytic Hydrolysis of Aminonitrile Process Technology

Methionine, one of the essential amino acids indispensable for the life activities of livestock and poultry, serves as a key building block for animal protein synthesis. Due to its generally low content in natural feed raw materials, almost all modern intensive livestock farming relies on exogenous methionine added artificially. Behind this seemingly small molecule lies a global market with large scale, high technical barriers, and a highly concentrated competitive landscape. This article will deeply analyze the market pattern and upstream-downstream industrial chain of methionine, sort out the mainstream synthetic technology routes, and focus on introducing an innovative technology - rare earth catalytic hydrolysis of aminonitrile process.

I. Methionine Market Analysis and Scale

During the forecast period from 2023 to 2030, the key factor driving the growth of the global methionine market is the increasing adoption of methionine as an animal feed additive by livestock manufacturers. According to Data Bridge Market Research analysis, the global methionine market size was USD 4.11 billion in 2022 and is expected to reach USD 6.45 billion by 2030, with a Compound annual growth rate (CAGR) of 5.8% during the forecast period from 2023 to 2030. In 2023, the "plant-based" segment will dominate the market, driven by growing awareness of vegan diets and increased focus on fitness and health.

II. Multi-Billion Dollar Market and Highly Concentrated Competitive Landscape

However, in sharp contrast to the huge market demand is its highly concentrated supply pattern. For a long time, most of the global methionine production capacity has been controlled by a few chemical giants, such as Evonik (Germany), Adisseo (France), and Novus (USA). The formation of this oligopolistic structure stems from the extremely high technical and capital barriers of methionine production.

III. Market Characteristics

Cyclical Fluctuations

Methionine prices show obvious cyclical fluctuations affected by raw material costs (such as propylene, natural gas, sulfur), industry operating rates, downstream livestock industry prosperity (such as avian influenza, pig cycle), and global trade policies.

Strategic Material Attribute

As a key additive to ensure stable production in the livestock industry, the supply chain security of methionine has been regarded as a strategic issue by many countries, which also promotes major consumer countries such as China to continuously pursue technological independence and production capacity breakthroughs.

Diversified Product Forms

In addition to traditional solid methionine (DL-Methionine), liquid hydroxy methionine (MHA) has been increasing its market share due to its convenience in use and high absorption efficiency, becoming another dimension of technological competition.

IV. Upstream-Downstream Industrial Chain

The industrial chain of methionine is clearly divided into three links: upstream, midstream, and downstream.

Upstream: Supply of Basic Chemical Raw Materials

The main raw materials for methionine production are derived from petroleum and natural gas chemicals, including:

  • Propylene: Used for acrolein synthesis.
  • Methanol: Used for hydrocyanic acid synthesis.
  • Sulfur: Used for methanethiol synthesis.
  • Natural gas (methane): A raw material for another synthesis route of hydrocyanic acid and methanethiol.

Therefore, the cost competitiveness of methionine manufacturers is closely linked to global energy and chemical raw material prices, and enterprises with integrated industrial chain advantages have stronger risk resistance capabilities.

Midstream: Methionine Synthesis and Manufacturing

This is the link with the most concentrated technical, capital, and environmental protection requirements, and also the core of this article. In this link, enterprises convert simple inorganic/organic molecules from the upstream into high-value-added methionine products through complex chemical synthesis processes (see Part V for details).

The production process involves high temperature, high pressure, and highly toxic raw materials (such as hydrocyanic acid), which have extremely high requirements for process safety, conversion rate, three-waste treatment, and economy.

Downstream: Feed Additives and Terminal Livestock Industry

The synthesized methionine products are mainly (about 95%) used in the feed additive field, and are directly sold to large feed production enterprises or breeding groups.

Finally, they enter the breeding links of poultry, pigs, ruminants, and aquatic animals through feed, promoting animal growth, improving feed conversion rate, and ensuring health. A small portion of high-purity methionine is also used in the pharmaceutical and food industries.

V. Mainstream Synthetic Technology Routes and Challenges

Currently, the mainstream technology for industrial methionine production worldwide is the Hydantoin Process.

The Hydantoin Process is a very classic synthesis route, whose core steps include:

Reaction of acrolein with methanethiol and hydrocyanic acid: Generating 3-methylthiopropanal (MMP).
Reaction with hydrocyanic acid and ammonium carbonate (or sodium cyanide, carbon dioxide): Condensation of MMP with the above substances to form 5-(2-methylthioethyl) hydantoin (Hydantoin).
Hydrolysis: Hydantoin is hydrolyzed under alkaline or acidic conditions to open the ring and generate sodium methionine (or methionine), which is then subjected to post-treatment processes such as acidification, crystallization, and drying to obtain the final product.

After decades of optimization, the Hydantoin Process has mature technology and stable yield, but its drawbacks have become increasingly prominent:

Lengthy Steps

Numerous reaction steps, complex process, and huge equipment investment.

Highly Toxic Raw Materials

A large amount of extremely dangerous chemicals such as hydrocyanic acid (HCN) are used throughout the process, requiring extremely high standards for safe production, storage, and transportation.

Three-Waste Problems

A large amount of cyanide-containing wastewater and high-salt organic wastewater are generated during the production process, which are difficult to treat and have high costs, resulting in huge environmental protection pressure.

Cost Pressure

Dependence on multiple raw materials makes its cost vulnerable to fluctuations in commodity prices.

These pain points have spurred the industry to explore new synthesis routes that are simpler, safer, and more environmentally friendly.

VI. Rare Earth Catalytic Hydrolysis of Aminonitrile Process

 Click to Learn More About the Detailed of Rare Earth Catalytic Hydrolysis of Aminonitrile Process

1. Hydrogen Sulfide Process

  • Industry-leading technology for producing high-purity liquid hydrogen sulfide from carbon disulfide.
  • Reduces the use of hydrogen sulfide compressors and minimizes methanethiol by-products.

2. Methanethiol Process

  • Integrates imported methanethiol catalysts to optimize the methanethiol production process.
  • Uses high-purity liquid hydrogen sulfide to reduce by-products.

3. Acrolein Process

  • Adopts proprietary and mature acrolein production technology with more advanced performance.
  • Recovers industrial acrylic acid using by-product acrylic acid, solving the pain point of difficult treatment of industrial waste liquid.

4. Methylthiopropanal Process

  • Optimizes the synthesis of methylthiopropanal using Dodgen's advanced pipeline reactor technology.

VII. Conclusion

The methionine market is advancing amid the contradiction between rigid demand growth and existing technical bottlenecks. Although the Hydantoin Process still dominates the current market, its challenges in safety, environmental protection, and cost have left huge room for innovators.

DODGEN's rare earth catalytic hydrolysis of aminonitrile process represents a way of thinking to reshape the industrial pattern through basic chemical innovation. It is not a patchwork of the old process, but a fundamental reconstruction from the perspective of reaction routes and catalytic science. Although this technology still faces challenges such as engineering scaling-up, catalyst life and recovery, and long-term stability when moving from the laboratory to 10,000-ton scale industrial production, its demonstrated great potential is sufficient to shake the industry.

In the future, competition in the methionine market will be a competition of comprehensive strength, a multi-dimensional contest of cost, safety, environmental protection, and technology. Innovative technologies like DODGEN's are not only expected to open a breakthrough for latecomers to enter the market, but also will force the entire industry to carry out technological upgrading, promoting the global methionine industry to evolve in a safer, greener, and more efficient direction. Whoever can take the lead in mastering and applying the next-generation synthesis technology on a large scale will occupy a dominant position in the future pattern of this multi-billion dollar market.