FAQ

Taking biobased succinic acid as an example, the content of succinic acid produced in the fermentation broth is only a few percent, and the concentration is quite low. At the same time, the components inside are relatively complex, and it dissolves in the fermentation broth. The boiling point of succinic acid is high, extremely sensitive, and easy to form anhydride when heated, making separation difficult. However, DODGEN's treatment plan is to first esterification the fermentation broth to produce dimethyl succinate, and then distill/distill the dimethyl succinate from the reaction broth Here, obtain the preliminary concentrated dimethyl succinate. By further coupling crystallization, dimethyl succinate with a purity of over 99.5% was obtained. Dimethyl succinate can be further hydrogenated to generate BDO, or directly reacted with BDO to obtain a biodegradable material PBS, which is also a hot topic for future biodegradable materials.

The biochemical industry is infiltrating into the traditional chemical industry and shows an accelerating trend. At present, the biochemical industry has partially replaced the traditional chemical industry, such as bioethanol, amino acid, lactic acid, succinic acid, biological nylon, biopolymer materials, etc. With the further development of synthetic biology, the proportion of the biochemical industry replacing the traditional chemical industry will gradually increase, and I think the pace will be faster. Although the biochemical industry has The synthesis conditions are mild and chiral homogeneous substances can be obtained, especially in the field of drug synthesis, which do not rely on fossil energy (resources) and other advantages. However, the crude products synthesized by biochemical synthesis often have disadvantages such as low concentration, complex components, and difficult separation and purification. This puts forward updated and higher requirements for traditional chemical separation technologies. Biochemistry requires new separation technologies with the ability to finely separate multiple components from crude products, resulting in different types of biochemicals; Due to the presence of heat sensitive substances in biochemical reactions, separation techniques are required to be able to separate at relatively low temperatures to reduce the occurrence of side reactions. At present, biochemical engineering is developing rapidly, and I believe it is also the future trend of green chemical engineering (green synthesis), and a strong supplement to the traditional chemical industry.

Whether it's bio based materials, chemicals, or functional chemicals, in terms of the process of biosynthesis (biochemistry), it's not just a process of biosynthesis, but also a traditional natural biological process that combines biochemistry (natural biological cycle) The concept of "separation" is introduced into large-scale industrial production processes, which is a systemic issue that needs to be considered from the perspective of the overall system, including the core technical bottleneck. From the perspective of natural circulation separation, due to the characteristics of its own biosynthetic system, its separation is, in my opinion, the biggest technical bottleneck in biochemistry.

DSV-Type High-Efficiency Mixer: Typically used for gas-gas, gas-liquid, liquid-liquid material absorption, mixing, and reaction processes with low material viscosity (viscosity ≤ 102). It is particularly suitable for mass transfer between clean media.

DSX-Type High-Efficiency Mixer: Generally employed for gas-gas, gas-liquid, liquid-liquid material mixing, and reaction processes, known for its wide applicability and uniform mixing characteristics.

DSXL-Type High-Efficiency Mixer: Typically applied for heat transfer, mixing, and forced heat exchange of materials with high viscosity (viscosity ≤ 106) and polymer materials. It is often used in multi-tube configurations, especially in the field of polymer devolatilization.

DSK-Type High-Efficiency Mixer: Usually used for mixing, reaction, and heat transfer processes involving materials with high viscosity (viscosity ≤ 106) in liquid-liquid and solid-liquid applications. It is particularly suitable for low-flow applications with impurities in viscous media.

The static mixer is an efficient mixing device that does not contain moving parts. It is widely used for continuous and efficient pipeline mixing, and different mixing requirements and material characteristics require the selection of different types and quantities of mixing unit components to disperse different materials individually, mix them with each other, and achieve the purpose of good dispersion and thorough mixing between materials.

Packing material optimizes chemical separation, also known as mass transfer, by providing a large wetted surface area. During the process of mass transfer, separation is typically achieved through the contrasting forces of heat and pressure against gravity. Heat and pressure drive water vapor upwards while gravity causes liquid substances to move downward. Packing material amplifies these forces, facilitating a faster and more efficient chemical separation process.

Random packing employs randomly distributed small packing materials to assist in the separation process, whereas structured packing utilizes larger, fixed packing structures. These more organized materials guide liquid substances through intricate structural passages, forming specific and stable shapes.

Random packing is used in separation columns, such as distillation columns, to increase the surface area for vapor/liquid contact, thereby enhancing chemical separation efficiency. In a distillation column, small pieces of random packing are designed to create a large surface area where reacting substances can interact with each other while minimizing the complexity within the column. The purpose of random packing is to maximize the surface area-to-volume ratio and minimize pressure drop.

Most separation processes require the use of random packing. The primary advantage of random packing is its significantly lower cost compared to structured packing. Other benefits of random packing include the ability to improve surface area, mass transfer, and efficiency at a relatively lower cost compared to traditional techniques such as tray technology. In addition to the applications discussed above, random packing is also used in applications like stripping, distillation, carbon dioxide adsorption, and liquid-liquid extraction.

Sometimes the structure provided by random packing may not be sufficient, and in such cases, structured packing is used. Structured packing is an organized type of packing used to guide liquid into specific shapes. It consists of discs made from materials like metal, plastic, or ceramics, arranged internally in various types of honeycomb-like patterns that remain consistent within the column. Structured packing columns are intricately designed to provide a large contact surface for liquids while minimizing resistance that could impede liquid flow.

In packed columns, creating opportunities for contact between liquids and gases is crucial. One effective approach is using packing that allows liquids to spread into thin films. This configuration increases contact and enhances performance. Certain types of structured packing materials also feature additional textural designs to facilitate liquid spreading. Liquid spreading is particularly important in low-pressure applications, where relying solely on internal pressure may not ensure proper liquid distribution.

The advantage of random packing lies in its high cost-effectiveness. If high capacity and lower efficiency, with cost being a limiting factor, then random packing offers quality performance at a lower price point.

Structured packing is employed in applications that require high capacity and efficiency. When high capacity is a critical requirement, the intricate internal structure of structured packing allows for a significantly larger surface area, achieving extremely high capacity. The smooth honeycomb form of structured packing minimizes hindrance to liquid flow, thus enhancing efficiency. Structured packing can also be used in scenarios requiring low pressure drop, as it generally offers lower pressure drop compared to random packing.

DODGEN micro reactor is suitable for highly exothermic rapid reactions with a small liquid holdup, rapid mass and heat transfer, avoiding the "temperature runaway" phenomenon, ensuring high safety. It enables parallel scale-up of tubular reactions without amplification effects, supporting continuous reactions with minimal side effects，enhancing selectivity, and achieving high conversion rates. Additionally, we have stainless steel small-scale and pilot-scale equipment available for customer experimentation.

DODGEN polymerization reactor is capable of handling a wide range of viscosity distributions in polymerization reactions. It can accurately control the temperature inside the reactor，reduce side reactions, eliminate dead region, and ensure uniform distribution. It can produce polymer products of different grades in separate reaction zones, enabling precise and independent process temperature control. It can operate continuously, ensuring stable product quality, low pressure drop, and minimal maintenance costs, all without the need for agitation equipment.

An extraction tower, also known as a liquid-liquid extraction column, is a vital piece of industrial equipment utilized in the process of liquid-liquid extraction. This process is a method to separate compounds based on their relative solubilities in two different immiscible liquids, usually water and an organic solvent.

The extraction tower is a vertically oriented, cylindrical apparatus designed to facilitate the efficient mixing and separation of these two phases. The mixture to be separated is introduced along with the solvent at different points in the tower. The design of the tower allows for a large surface area between the two immiscible liquids, promoting the transfer of solute from the feed mixture to the solvent.

The extraction tower is engineered to maximize contact between the phases, often through the use of trays or packing material to increase turbulence and thus enhance mass transfer. The separated components are then collected at different exit points. The choice of extraction tower design and operation parameters depends on the properties of the substances to be separated, the characteristics of the solvent used, and the required throughput.